Metamfetamin v pre-workout boosterjih (Craze, Detonate ...)

As a follow up to our previous post on this subject, Predator Nutrition is concerned to hear that fitness pro Rob Riches is alleging that his failure on a drugs test was due to his apparent use of Craze and is blaming the product for this. It is odd that this should happen since the product clearly states that it should not be used by tested athletes – for the simple reason that doping tests can produce false positives such as this one.

We cannot understand why anyone would refuse to follow manufacturer guidelines that are on the label for this exact reason.

If we leave aside the widely held feeling of people in the industry that a star athlete has been given a convenient scapegoat to enable him to proclaim his innocence (an accusation made by fellow competitors who assert that they have used Craze and been subjected to the same testing without any problems) let’s look at his own supposition more closely.

Given the wide number of substances any fitness professional uses it is impossible to verify in the human body what could have caused this although a preliminary investigation shows the testing conducted was quite basic and would not be able to distinguish between multiple similar looking susbstances.

We address many of the problems with not just this test but others in our previous post, but what you have is basic test procedures and a failure to follow anything resembling a proper chain of custody, nor have any tests conducted showing alleged unclassified substances ever produced a reference standard first to correctly identify the compounds being flagged in tests. This leads to misidentification of compounds with similar chemical structures but which, upon further extensive testing involving a correctly produced reference standard are shown not to exist after all.

To date every single “positive” test on units fail to show a chain of custody back to Driven Sports nor did such tests take appropriate measures to ensure no misidentification of compounds could occur. None of the tests have been to the level of rigor required to properly separate fact from fiction in terms of correct classification of different substances in Craze.

We have seen a number of rival companies and retailers talk up this problem for their own reasons. Driven Sports have spent hundreds of thousands on testing of Craze to ensure it is safe and conforms to all label claims with a level of testing rigour not evidential elsewhere and that includes this Rob Riches test.

For an example of this, and the type of testing that should be conducted we refer readers to the below. A white paper on correct procedures to test Craze will follow shortly from a non-affiliated body and once those are established the confusion which reigns now will dissipate and we believe Craze will be vindicated. When that paper is published we believe any world class laboratory following the correct protocols will be able to determine the same for themselves.

UPDATE: We now hear that he claims to have used the product one whole week before his event which would be more than enough time for any such substance which he tested positive for to clear from his system….

It looks like this is a sorry case indeed where even if the substance was somehow, magically, to be found in Craze despite the 30+ reports saying otherwise, he should still not have tested positive for it which leaves the likelihood of a cover-up (very common in professional sport, let alone bodybuilding).

Haha Patrick Arnold na FB:

Patrick Arnold
Tyson gay popped for something in a mystery cream given to him by a chiropractor. Some guy named Clayton Gibson from atlanta?

Patrick Arnold Powell and Jamaicans were caught with methylsynephrine

Glede Craze-a, zdaj je bolj kot ne tudi "uradno" potrjeno:

A methamphetamine analog (N,α-diethylphenylethylamine)identified in a mainstream dietary supplement

Pieter A. Cohen,a* John C. Travisb and Bastiaan J. Venhuisc

Pharmaceuticals and banned substances have been detected in hundreds of purportedly natural supplements. Recently, several athletes have been disqualified from competition after testing positive for the methamphetamine analog N,α-diethyl-phenylethylamine (N,α-DEPEA). Athletes have claimed they unknowingly consumed the banned stimulant in workout supplements. Three samples from different lot numbers of Craze, a workout supplement, were analyzed to detect the presence and concentration of N,α-DEPEA. Two labs independently identified N,α-DEPEA in the supplement usingultra high performance liquid chromatography (UHPLC) coupled to an LTQ Orbitrap XL mass spectrometer and UHPLCquadruple-time-of-flight mass (Q-TOF) spectrometer, respectively. The identity of N,α-DEPEA was confirmed using nuclearmagnetic resonance and reference standards. Manufacturer recommended servings were estimated to provide 21 to 35mg ofN,α-DEPEA. N,α-DEPEA has never been studied in humans. N,α-DEPEA is a methamphetamine analog; however,its stimulant, addictiveand other adverse effects in humans are entirely unknown. Regulatory agencies should act expeditiously to warn consumersand remove N,α-DEPEA from all dietary supplements.

Copyright © 2013 John Wiley & Sons, Ltd.

http://onlinelibrary.wiley.com/doi/10.1002/dta.1578/pdf